Linkage Projects - Grant ID: LP250100335 [ 2026-01-01 - 2028-12-31 ]

Research Grant

Researchers: Professor Damian Hine (Chief Investigator) ,  Professor Gary Schenk (Chief Investigator) ,  Professor Luke Guddat (Chief Investigator) ,  Professor Mikael Boden (Chief Investigator) ,  Mr Joe Ley (Partner Investigator)
View all 7 related researchers

Brief description Synergistic industry partnership for bioproduction of platform chemicals. Isobutanol is an attractive chemical for the manufacture of a range of products (e.g. rubber, aviation fuels), but has yet to reach competitive yields and pricing. This project integrates the pioneering technique of ancestral sequence reconstruction, in combination with AI, to engineer biocatalysts for the competitive production of isobutanol using both cell-free reaction cascades and fermentative processes. The scalability and commercial impact of both production pathways will be monitored by technoeconomic analyses. This project aims to deliver a rapid pipeline for the design of optimal biocatalysts for sustainable bioproduction processes, will generate valuable IP and contribute to the growth of the aviation fuel industry in Australia.

Funding Amount $630,206

Funding Scheme Linkage Projects

View this grant in the ARC Data Portal