Research Grant
[Cite as https://purl.org/au-research/grants/arc/LP140100920]Researchers: Prof Dale Godfrey (Chief Investigator) , Prof Jamie Rossjohn (Chief Investigator) , Nikolai Petrovsky (Partner Investigator)
Brief description Exploring the immunomodulatory potential of Natural Killer T cells. Natural Killer T cells (NKT cells) are an innate-like population of T cells that recognise a range of lipid based antigens when bound to the antigen-presenting molecule, CD1d. Once activated, NKT cells rapidly secrete a variety of cytokines. This project, in partnership with Vaxine Pty Ltd, aims to gain a basic understanding of NKT recognition of lipids and NKT cell activation by lipids. The project aims to use a combination of cellular immunology and structural biology to gain insight into NKT cell agonism.
Funding Amount $590,922
Funding Scheme Linkage Projects
- PURL : https://purl.org/au-research/grants/arc/LP140100920
- ARC : LP140100920