A Lineage Specific Pathway for Progression of Melanoma [ 2007 - 2009 ]

Research Grant

Researchers: Dr Glen Boyle (Principal investigator) ,  Dr Geoff Strutton ,  Prof Peter Parsons

Brief description Melanoma is an insidious cancer, and its incidence has increased dramatically over the past four decades. Melanoma has an almost universally poor prognosis once metastasis has occurred. There are currently no treatment regimens that have a significant impact on prolonging survival or decreasing mortality from metastatic melanoma. Our preliminary data has shown the importance of a factor found in normal melanocytes in control over expression of a separate factor required for invasion and metastasis of melanoma. These markers could serve as an important diagnostic marker for melanoma. Further, they may be suitable drug targets for the prevention and treatment of metastatic melanoma, and will advance our understanding of how melanoma spreads.

Funding Amount $AUD 485,746.74

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant