Lamstatin- a novel inhibitor of lymphangiogenesis [ 2011 - 2013 ]

Research Grant

Researchers: Prof Judy Black (Principal investigator) ,  Dr Lyn Moir ,  Dr Markus Weckmann

Brief description We have discovered that part of a collagen molecule - lamstatin- inhibits growth of lymphatic cells and their communicating networks. Excessive lymphatic growth occurs in lymphangioleiomyomatosis (LAM)- a fatal disease which affects young women- and many cancers. We have shown that lamstatin prevents growth of lymph vessels in a skin tumour in mice and we will investigate if it can prevent spread of tumours to other organs which has exciting implications for the treatment of cancer.

Funding Amount $AUD 659,494.63

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant