grant

Investigation of a new hypothesis that increased TGF? activity in developing fetal organs predisposes a women to polycystic ovary syndrome and associated metabolic disorders [ 2013 - 2016 ]

Also known as: Investigation of a new idea that what happens in fetal life can determine the risk of developing polycystic ovary syndrome when an adult.

Funded by National Health and Medical Research Council
Managed by University of Adelaide
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1051720]

Researchers: Prof Raymond Rodgers (Principal investigator) ,  Prof Richard Anderson

Brief description Have you ever wondered why some people get fat and other do not, no matter how much they eat? The answer could lie in what happened before they were born. This project investigates a new hypothesis that was developed from discoveries on polycystic ovary syndrome. Women with this syndrome are at increased risk of becoming overweight and diabetic. If the hypotheses prove correct it might be possible to reduce the incidence of these metabolic disorders in the longer term.

Funding Amount $AUD 583,015.95

Funding Scheme Project Grants

Notes Standard Project Grant

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Subjects
Foetal Development and Medicine | Medical and Health Sciences | Paediatrics and Reproductive Medicine | fetal origins of disease | fetal programming | fibrillin | fibrosis | insulin resistance | metabolic syndrome | polycystic ovarian syndrome (PCOS) | stroma | transforming growth factor beta (TGF-beta) |
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