grant

Investigation of a New Approach to Regulate Fibrin Clot Retraction and Arterial Thrombolysis [ 2010 - 2012 ]

Also known as: A novel approach to dissolving blot clots

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/606580]

Researchers: Prof Shaun Jackson (Principal investigator) ,  A/Pr Simone Schoenwaelder

Brief description Pathological blood clots are removed in patients by administering clot dissolving drugs (fibrinolytics). However these drugs are quite often ineffective and cause bleeding. We have identified a new platelet-mediated pathway controlling contraction of blood clots, important for clot stability. In this proposal, we will examine the potential for inhibitors of this pathway to loosen blood clots, and facilitate the actions of fibrinolytics to promote clot dissolution.

Funding Amount $AUD 483,171.09

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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