Investigation into host susceptibility and immune responses in young children with acute wheezing due to human rhinovirus group C infection [ 2013 - 2015 ]

Also known as: Acute severe wheezing attacks due to human rhinovirus group C infection in young children: risk factors for these attacks, immune responses during the attack and subsequent outcome.

Research Grant

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Researchers: Prof Peter Le Souef (Principal investigator) ,  Dr Andrew Currie Dr Gary Geelhoed A/Pr Belinda Hales A/Pr Guicheng Zhang
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Brief description We recently made the surprising discovery that a new viral group, human rhinovirus group C (HRV-C), causes the majority of acute asthma in children. We also found that it causes half of the acute wheezing attacks in younger children, and is the only respiratory virus associated with allergy. So, HRV-C may be the key to the relationship between allergy and asthma. The planned project will focus on whether young children who wheeze with HRV-C have related defects in their immune system.

Funding Amount $AUD 682,711.08

Funding Scheme Project Grants

Notes Standard Project Grant

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