Investigation into host susceptibility and immune responses in young children with acute wheezing due to human rhinovirus group C infection [ 2013 - 2015 ]

Research Grant

Researchers: Prof Peter Le Souef (Principal investigator) ,  A/Pr Belinda Hales ,  A/Pr Guicheng Zhang ,  Dr Andrew Currie ,  Dr Gary Geelhoed
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Brief description We recently made the surprising discovery that a new viral group, human rhinovirus group C (HRV-C), causes the majority of acute asthma in children. We also found that it causes half of the acute wheezing attacks in younger children, and is the only respiratory virus associated with allergy. So, HRV-C may be the key to the relationship between allergy and asthma. The planned project will focus on whether young children who wheeze with HRV-C have related defects in their immune system.

Funding Amount $AUD 682,711.08

Funding Scheme Project Grants

Notes Standard Project Grant