grant

Investigation of the functional role of antibodies against myelin proteolipid protein in multiple sclerosis [ 2014 - 2017 ]

Also known as: Do antibodies against myelin proteolipid protein play a role in multiple sclerosis?

Funded by National Health and Medical Research Council
Managed by The University of Queensland
Managed by University of Queensland
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1063170]

Researchers: A/Pr Judith Greer (Principal investigator) ,  Prof Michael Pender

Brief description There is a lot of suggestive evidence that molecules called antibodies might cause a faster progression of disease in people with multiple sclerosis (MS), but this remains to be proven. The proposed study will investigate the mechanisms by which antibodies could hasten MS disease progression. Results of this study will help inform treatment options for people with MS and will also help us to better understand the basic pathogenic mechanisms that can cause MS.

Funding Amount $AUD 626,174.76

Funding Scheme Project Grants

Notes Standard Project Grant

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Subjects
Clinical Sciences | Clinical Sciences Not Elsewhere Classified | Medical and Health Sciences | antibody | axonal injury | demyelinating disease | demyelination | multiple sclerosis (MS) | pathogenic mechanisms | signalling pathways |
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