grant

Investigation into the alternative splicing of steroid hormone regulated genes in breast cancer. [ 2008 - 2010 ]

Also known as: To understand how and why steroid hormones are able to make different proteins from a single gene in breast cancer cells

Funded by National Health and Medical Research Council
Managed by The University of Queensland
Managed by University of Queensland
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/511153]

Researchers: Dr Dennis Dowhan (Principal investigator)

Brief description Steroid hormones have imortant roles in breast tissue growth and differentiation. We have identified several proteins called PRMT6 and CAPER's , that are involved in steroid hormone signaling and control the alternative splicing of RNA, the process in which several different proteins can be produced from a single gene. Our aim is to study these proteins in an effort to understand how they influence alternative splicing and to identify genes they control in relation to breast cancer.

Funding Amount $AUD 292,216.81

Funding Scheme NHMRC Project Grants

Notes New Investigator Grant

Click to explore relationships graph
Help

Related Organisations

Related People

Subjects
270201 | Biochemistry and molecular biology | Cancer biology | Control of gene Expression | Gene expression | Molecular Mechanisms | RNA binding proteins | RNA processing | Steroid hormone receptors | post-transcriptional regulation of gene expression | steroid hormone action |
Identifiers
Viewed: [[ro.stat.viewed]]
Saved to MyRDA Save to MyRDA