[Cite as http://purl.org/au-research/grants/nhmrc/509693]
A/Pr Ross Dickins
Brief description Inhibiting gene expression using the recently discovered process known as RNA interference (RNAi) can be used as an experimental tool to analyse specific genes, in cells and genetically engineered animal models of human disease. I propose to use RNAi to mimic human cancer gene mutations in mouse cancer models, and aim to discover novel tumour suppressor genes. A further aim is to validate potential drug targets in cancer by using RNAi to inhibit specific genes in established mouse tumours.
Funding Amount $AUD 305,915.00
Funding Scheme Career Development Fellowships
RD Wright Biomedical CDF