Investigating mechanisms of axonal pathology following oligodendrocyte apoptosis: avenues for neuroprotection in early MS [ 2014 - 2016 ]

Research Grant

Researchers: Dr Tobias Merson (Principal investigator) ,  Prof Trevor Kilpatrick

Brief description Recent research suggests that Multiple Sclerosis could first be triggered by the death of a type of brain cell called an oligodendrocyte. These cells insulate nerve cells in the brain which help them function normally. We will test the idea that death of oligodendrocytes impairs nerve cell function by causing inflammation and by depriving nerve cells of energy. We will determine whether preventing inflammation and feeding the nerve cells an alternative source of energy can restore normal function.

Funding Amount $AUD 678,138.42

Funding Scheme Project Grants

Notes Standard Project Grant