grant

Investigating the host determinants of viral clearance versus collateral pathology in chronic infection [ 2014 - 2017 ]

Also known as: Defining factors that can help eradicate chronic viral infection and prevent damage of host tissues

Funded by National Health and Medical Research Council
Managed by The Walter and Eliza Hall Institute of Medical Research
Managed by Walter and Eliza Hall Institute
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1065626]

Researchers: Prof Marc Pellegrini (Principal investigator) ,  A/Pr Peter Revill

Brief description Hepatitis B virus has infected over 2 billion people. Some people control the virus but it remains incurable and there is a lifelong risk of liver cancer. Understanding how host cells interact with the virus, the mechanisms the cells use in an attempt to eliminate the virus and the mechanisms the virus uses to sabotage these responses, will provide insights that could lead to therapies. Potential therapies could be applicable to other infections like HIV-1 and tuberculosis.

Funding Amount $AUD 1,250,756.09

Funding Scheme Project Grants

Notes Standard Project Grant

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Subjects
Medical and Health Sciences | Medical Microbiology | Medical Virology | apoptosis | cell death | hepatitis B infection | hepatitis B virus | liver cancer | microbiology | molecular pathogenesis | necrosis | pattern recognition | virology |
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