grant

Investigating drug treatments for a Machado Joseph disease using transgenic zebrafish [ 2014 - 2017 ]

Also known as: Seeking a cure for Machado Joseph disease – a prevalent neurodegenerative disease within Aboriginal communities of northeast Arnhem Land

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1069235]

Researchers: Dr Angela Laird (Principal investigator) ,  Prof Thomas Becker Dr Jean Giacomotto Prof Garth Nicholson

Brief description Machado Joseph disease (MJD) is a hereditary neurodegenerative disease that causes problems with a patient’s co-ordination and movement, leading to paralysis and death. Although the disease affects patients throughout the world, it is most common within Aboriginal communities of Arnhem Land in the Northern Territory. This project seeks to identify a drug treatment for the disease by examining the effect of relevant drugs on zebrafish genetically modified to have the human gene that causes MJD.

Funding Amount $AUD 443,425.26

Funding Scheme Project Grants

Notes Standard Project Grant

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