Investigating the aetiopathogenic role of autoantibodies against the M1 muscarinic acetylcholine receptor in patients with first episode of schizophrenia [ 2016 - 2020 ]

Research Grant

Researchers: A/Pr Judith Greer (Principal investigator) ,  A/Pr James Scott ,  Prof Bryan Mowry

Brief description Previously we have found that a proportion of patients with schizophrenia have elevated levels of antibodies that target one of the neurotransmitter receptors, the M1 muscarinic acetylcholine receptor, and that those patients who have the highest levels of antibodies tend to have more severe manifestations of some of the symptoms of schizophrenia. In this project, we will try to confirm this relationship, and also investigate further how this antibodies might be able to worsen specific symptoms.

Funding Amount $AUD 859,910.46

Funding Scheme Project Grants

Notes Standard Project Grant