grant

How intra-abdominal transplantation of subcutaneous adipose tissue prevents high-fat diet-induced insulin resistance and obesity [ 2012 - 2014 ]

Also known as: Beneficial effects of subcutaneous fat transplantation

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1031769]

Researchers: Dr Michael Swarbrick (Principal investigator) ,  Dr Amanda Brandon Dr Samantha Hocking

Brief description In obese humans, storing excess fat within the abdomen is associated with the development of adult-onset diabetes and cardiovascular disease. However, the mechanisms linking intra-abdominal fat accumulation with these diseases are not well understood. We have studied intra-abdominal fat accumulation in mice using a transplant model, and we have found that transplanting subcutaneous fat intra-abdominally prevents diet-induced obesity and glucose intolerance. We aim to investigate the underlying mechanisms.

Funding Amount $AUD 358,465.54

Funding Scheme Project Grants

Notes New Investigator Grant

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