Interleukin 37 – a Novel Cytokine Therapy for Necrotizing Enterocolitis in the Preterm [ 2018 - 2020 ]

Research Grant

Researchers: Dr Claudia Nold (Principal investigator) ,  A/Pr Christiane Theda ,  A/Pr Marcel Nold ,  A/Pr Sebastian King

Brief description Neonatologists are adept at keeping extremely premature babies alive. But the price is a rising incidence of life-threatening diseases that include necrotising enterocolitis (NEC), a progressive and destructive intestinal inflammation that may require surgery, after which just 30% survive. We have created highly potent variants of the anti-inflammatory molecule interleukin 37 whose actions will improve our understanding of NEC pathogenesis and reveal their therapeutic potential in NEC.

Funding Amount $AUD 759,331.86

Funding Scheme Project Grants

Notes Standard Project Grant