grant

Interleukin-1? biology: mechanisms of regulation, activation and secretion [ 2016 - 2018 ]

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1101405]

Researchers: Dr James Vince (Principal investigator) ,  Dr Seth Masters

Brief description The protein called intelreukin-1 (IL-1) is required to fight off invading pathogens but more recently has been implicated as contributing to diverse diseases characterised by excessive inflammation, such as arthritis, gout, atherosclerosis and even cancer. This project aims to understand how IL-1 is made within cells and then activated to cause inflammation, which will enable these processes to be therapeutically targeted.

Funding Amount $AUD 659,693.89

Funding Scheme Project Grants

Notes Standard Project Grant

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