grant

Interactions between Transcription Factor Networks and Cell Signaling Pathways during Early Blood Development [ 2009 - 2011 ]

Also known as: Transcriptional regulation of early blood development

Funded by National Health and Medical Research Council
Managed by University of New South Wales
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/568668]

Researchers: Prof John Pimanda (Principal investigator) ,  A/Pr Marella De Bruijn ,  Prof Bertie Gottgens

Brief description Cancer initiating cells acquire stem cell characteristics and self renew within a supportive environment that helps maintain and propagate malignant tumours. Identifying the normal hierarchy of gene regulation within blood stem cells and designing therapies that target key transcription factors (proteins that control other genes) that are over expressed in cancer stem cells is the ultimate goal.

Funding Amount $AUD 589,338.34

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Subjects
270106 | Cancer stem cells | Cell signalling | Gene regulation | Haematopoiesis | Haematopoietic Stem Cells | Leukaemia | Myelo and lymphoproliferative disorders | Tissue regeneration | Transcription factor networks |
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