INTERACT: a randomised trial of intensive blood pressure lowering in acute intracerebral haemorrhage [ 2008 - 2011 ]

Also known as: BP lowering therapy to improve outcome from haemorrhagic stroke

Research Grant

[Cite as]

Researchers: Prof Craig Anderson (Principal investigator) ,  Prof Jiguang Wang Prof John Chalmers Prof Richard Lindley

Brief description Intracerebral haemorrhage (ICH) is a serious type of stroke affecting thousands of Australians and 2-3 million people in the world each year, with most either dying or left disabled. There is no proven treatment for ICH, although surgery is sometimes used and early injection of a special clotting factor may improve outcome. One potential simple therapy is the rapid control of elevated blood pressure (BP) which occurs commonly and predicts a poor outcome in ICH, possibly by increasing bleeding and swelling in the brain. There is much uncertainty as to the optimal management of elevated BP in ICH. This study, called INTERACT, aims to determine the balance of benefits and risks of a management strategy of early rapid BP lowering in 2000 patients with ICH randomised from 100 clinical sites in Australia-Asia.

Funding Amount $AUD 2,680,867.89

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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