Integrative bioinformatic and experimental approaches to define novel roles for genes that typically regulate Axon Guidance in pancreatic cancer initiation [ 2013 - 2015 ]

Research Grant

Researchers: Dr Ilse Rooman (Principal investigator) ,  Dr Jianmin Wu

Brief description Early detection and intervention would have a dramatic effect on improving the outcomes for pancreatic cancer. This however relies on understanding how the cancer is initiated. New analysis of more than 100 tumours identified aberrations in genes that typically regulate how the nervous system is positioned during development. We want to use novel bioinformatic approaches and a unique experimental method with cells in culture to rapidly and accurately find out which of these genes drives a normal pancreatic cell to become a tumour cell.

Funding Amount $AUD 587,955.76

Funding Scheme Project Grants

Notes New Investigator Grant