Integrating drug delivery principles into drug design to transform the treatment of immune disease [ 2011 - 2014 ]

Research Grant

Researchers: Prof Christopher Porter (Principal investigator) ,  A/Pr Frank Alderuccio ,  Dr Natalie Trevaskis ,  Prof William Charman

Brief description Immune system disorders (e.g. rheumatoid arthritis, transplant rejection, Crohn’s disease, multiple sclerosis) are often treated with immunosuppresant drugs. However, immunosuppressant drugs can cause significant toxicity and can lack efficacy. This proposal will show how the design of drugs used to treat immune disorders can be changed to allow drugs to be delivered specifically to their site of action (immune cells) thereby enhancing activity and reducing toxicity.

Funding Amount $AUD 552,635.75

Funding Scheme Project Grants

Notes Standard Project Grant