grant

Inhibitors of Secretory Phospholipases in Diet Induced Obese Rats [ 2010 - 2012 ]

Also known as: Investigating a new treatment for obesity induced diseases

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/631534]

Researchers: Prof David Fairlie (Principal investigator) ,  A/Pr Jonathan Whitehead Dr Robert Reid Prof Johannes Prins Prof Lindsay Brown

Brief description A new drug given to rats fed a high fat-carbohydrate diet shows very promising effects in preventing and treating abdominal obesity, insulin resistance, glucose intolerance, and other risk factors for diabetes and cardiovascular disease. This project will profile biochemical and pharmacological properties of the drug in more detail in order to track down molecular mechanisms of its action and potential therapeutic benefits, guided by studies on rats, biochemical markers, rat and human fat cells.

Funding Amount $AUD 581,051.65

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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