grant

Inhibitors Of Class II HDACs In Inflammatory And Metabolic Disease [ 2013 - 2015 ]

Also known as: New approaches to treat inflammatory, metabolic and obesity diseases

Funded by National Health and Medical Research Council
Managed by The University of Queensland
Managed by University of Queensland
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1047921]

Researchers: Prof Matthew Sweet (Principal investigator) ,  Dr Abishek Iyer ,  Prof David Fairlie

Brief description Inflammatory diseases such as arthritis and inflammatory bowel syndrome are major social and economic burdens on Australian communities. Obesity, diabetes and cardiovascular disease are also now widely viewed as inflammatory diseases. New specialised types of anti-inflammatory drugs are urgently needed to treat such diseases. This project proposes to create new classes of anti-inflammatory drugs by altering anti-cancer drugs called histone deacetylase inhibitors.

Funding Amount $AUD 615,773.98

Funding Scheme Project Grants

Notes Standard Project Grant

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Subjects
Immunology | Innate Immunity | Medical and Health Sciences | Toll-like receptors | drug design | histone deacetylase | inflammation | inflammatory bowel disease (IBD) | macrophages | medicinal chemistry | obesity | rheumatoid arthritis | transgenic mouse |
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