grant

Inhibition of Siderophore Biosynthesis for Tuberculosis Drug Discovery [ 2010 - 2012 ]

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/632769]

Researchers: Prof Richard Payne (Principal investigator) ,  Prof Warwick Britton

Brief description Tuberculosis (TB) is responsible for over 2 million deaths globally every year. Despite this alarming statistic, no new TB drugs have reached the market in 40 years. This is despite the emergence of strains of Mycobacterium tuberculosis (the causative agent of TB) that are resistant to currently prescribed drugs. This project aims to discover TB drug leads with a unique mode of action. This will be achieved by preparing compounds that prevent the bacterium from acquiring iron from the host.

Funding Amount $AUD 424,262.16

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857