Inhibition of haemostasis as a novel host-directed therapy for tuberculosis [ 2016 - ]

Research Grant

Researchers: Dr Stefan Oehlers (Principal investigator)

Brief description Mycobacterium tuberculosis-induced vasculopathy is an important cause of stroke worldwide, and stroke is a common (~20%) complication of tuberculous meningitis, the most dangerous presentation of tuberculosis. Blood clotting may also speed the growth tuberculosis in the body further worsening the situation. We will use zebrafish find out if clotting can be targeted to slow the growth of mycobacteria and then translate our findings to a mouse model of pulmonary tuberculosis.

Funding Amount $528,471.00

Funding Scheme Project Grants

Notes New Investigator Grant