grant

Inhibition of glucose-stimulated insulin secretion by Protein Kinase C epsilon [ 2008 - 2010 ]

Also known as: Insulin secretion defects in diabetes

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/481340]

Researchers: Prof Trevor Biden (Principal investigator)

Brief description Type 2 diabetes is a chronic disease which occurs when the pancreas is unable to produce enough insulin for the body to cope with rising blood glucose levels after a meal, and is strongly linked to obesity. We have discovered that fat oversupply activates an enzyme in the pancreas causing defects in insulin release due to glucose. Inhibiting this enzyme helps overcome diabetes, through poorly defined mechanisms that we aim to clarify here. Our work could lead to new therapies for diabetes.

Funding Amount $AUD 555,693.21

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857