grant

Inhibiting tumour growth by targeting EphA3 and disrupting tumour stromal and vascular microenvironment [ 2013 - 2015 ]

Also known as: Targeting EphA3 to inhibit tumour growth

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1049942]

Researchers: A/Pr Martin Lackmann (Principal investigator) ,  Dr Peter Janes (Principal investigator) ,  Dr Mary Vail Prof Andrew Elefanty

Brief description Tumours consist of cancer cells, tumour blood vessels and connective tissue, all of which are different to normal tissues. Many of the cells making up tumour vessels and connective tissue are recruited, during initial growth and subsequent spreading of tumours, from the bone marrow. Our research will examine the presence and function of the EphA3 receptor on these cells during tumour development and assess how our anti-EphA3 antibody inhibits tumour growth by targeting stroma and vasculature.

Funding Amount $AUD 645,136.03

Funding Scheme Project Grants

Notes Standard Project Grant

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