Increased airway smooth muscle mass as an independent determinant of asthma pathogenesis and severity [ 2012 - 2015 ]

Research Grant

Researchers: Dr Peter Noble (Principal investigator) ,  A/Pr Alexander Larcombe ,  A/Pr Graeme Zosky ,  A/Pr Timothy Lecras ,  Prof Alan James

Brief description Asthma is a major health burden to the community. The most common form of the disease is allergic asthma and it is thought that allergic inflammation drives associated airway abnormalities including increased airway smooth muscle (ASM) mass. This study tests a new hypothesis that airway abnormalities and allergy have separate origins but combine to produce allergic asthma, and it’s the individuals with the greatest amount of ASM who develop clinically severe asthma.

Funding Amount $AUD 409,966.08

Funding Scheme Project Grants

Notes Standard Project Grant