In-depth association and functional studies assessing the role of novel single nucleotide polymorphisms in PSA and other Kallikrein genes in prostate cancer.

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1009458]

Researchers: Prof Judith Clements (Principal investigator) , Dr Jyotsna Batra , Prof Amanda Spurdle

Brief description The number of men diagnosed with prostate cancer varies substantially between races, indicating a role of genetics in prostate cancer development. Recently, we demonstrated that the genetic variations in the PSA gene are related to prostate cancer risk. We aim to elucidate the molecular mechanism of this correlation and to systematically investigate the association of novel genetic variations in other PSA related genes with prostate cancer risk in a search of sensitive clinical biomarkers for prostate cancer diagnosis and prognosis.

Funding Amount $AUD 607,336.68

Funding Scheme Project Grants

Notes Standard Project Grant

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nhmrc : 1009458
PURL : https://purl.org/au-research/grants/nhmrc/1009458

In-depth association and functional studies assessing the role of novel single nucleotide polymorphisms in PSA and other Kallikrein genes in prostate cancer. [ 2011 - 2014 ]

Research Grant

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In-depth association and functional studies assessing the role of novel single nucleotide polymorphisms in PSA and other Kallikrein genes in prostate cancer. [ 2011 - 2014 ]

Research Grant

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