Improving cancer diagnostic imaging and drug delivery by breaking down extracellular matrix barriers [ 2017 - ]

Research Grant

Researchers: A/Pr Juliana Hamzah (Principal investigator) ,  Prof Erkki Ruoslahti ,  Prof Ruth Ganss

Brief description Solid tumours are stiffer than normal tissues. This stiffness is caused by over-production of non-cellular components known as extracellular matrix (ECM). ECM creates a barrier that restricts drug access in tumours. New methods to overcome tumour stiffness are crucial to improve drug delivery. We will study the use of a new compound to degrade tumour ECM to improve anti-cancer drug delivery. Our compound will be useful in treatment-resistant solid tumours such as breast and liver cancers.

Funding Amount $748,152.00

Funding Scheme Project Grants

Notes Standard Project Grant