grant

The Importance of p38 MAPK Signalling in Aging-Related Ischaemic Intolerance and Failed Cardioprotection [ 2008 - 2010 ]

Also known as: Effects of age on the hearts resistance to disease

Funded by National Health and Medical Research Council
Managed by Griffith University
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/481922]

Researchers: Prof John Headrick (Principal investigator) ,  A/Pr Jason Peart ,  A/Pr Kevin Ashton ,  A/Pr Salvatore Pepe

Brief description Ischaemic heart disease is the leading cause of death in Australia, and will rise in coming years with the aging of our population. Our research shows aged hearts become less resistant to damage during ischaemia-heart attack, and insensitive to normally beneficial therapies. This project will identify molecular changes responsible for these changes. By understanding how age impairs the hearts defences, it may be possible to improve therapy of ischaemic heart disease in older patients.

Funding Amount $AUD 496,302.85

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Subjects
Ageing | Ageing Disease | Aging | Biomedical and Clinical Sciences | Cardioprotection | Ischaemia-Reperfusion Injury | Ischaemic Heart Disease | MAP kinases | Myocardial Infarction | Myocardial Ischaemia | Nutrigenomics and Personalised Nutrition | Nutrition and Dietetics |
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