grant

The importance of GM-CSF in determining the fate and function of dendritic cell (DC) subsets: resident DC, inflammatory DC and suppressive DC. [ 2011 - 2013 ]

Also known as: GM-CSF acts differently on resident DC and monocyte-DC

Funded by National Health and Medical Research Council
Managed by The Walter and Eliza Hall Institute of Medical Research
Managed by Walter and Eliza Hall Institute
Provided by   National Health and Medical Research Council

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1007703]

Researchers: Dr Yifan Zhan (Principal investigator) ,  A/Pr Sammy Bedoui

Brief description The hormone GM-CSF determines how infections are seen by the immune system GM-CSF is a hormone already in use for increasing the production of white blood cells. We have found that it also affects their function, especially that of specialised white blood cells that process infectious materials to be recognised by the immune system. This project aims to detail the effects of GM-CSF on specialised white blood cells.

Funding Amount $AUD 334,053.95

Funding Scheme Project Grants

Notes Standard Project Grant

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Subjects
Cellular Immunology | Immunology | Medical and Health Sciences | autoimmunity | bacterial infection | cancer immunotherapy | cell activation | cell-mediated immunity | cytokines | dendritic cell | diabetes mellitus | molecular mechanisms |
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