Impact of a vaginal microbiota metabolite on epithelium integrity and HIV susceptibility [ 2019 - ]

Research Grant

Brief description Globally, 48% of the 1.8 million new HIV infections in 2016 are in young women in Africa where the virus mainly establishes infection by entry through the vagina. Women colonised with beneficial vaginal microbiota are protected against HIV in contrast to women with harmful vaginal bacteria. In this study we will investigate how a factor produced by beneficial microbiota augments the vaginal mucosal barrier to prevent HIV acquisition.

Funding Amount $864,418.00

Funding Scheme Project Grants

Notes Standard Project Grant