The impact of HIV integration sites on eliminating HIV latency [ 2014 - 2016 ]

Research Grant

Researchers: A/Pr Paul Cameron (Principal investigator) ,  Dr Dimitrios Vatakis ,  Prof Simon Mallal

Brief description Current antiviral therapy for HIV controls virus production and allows recovery but does not eliminate the silent infection that prevents complete virus elimination and cure. We will examine two ways that HIV can silently infect T cells for differences in the sites at which the HIV DNA inserts into the genome. We will examine the way in which these differences at the genomic level may limit the ability to activate and eliminate persistent infection in memory T cells.

Funding Amount $AUD 778,313.54

Funding Scheme Project Grants

Notes Standard Project Grant