Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/1007830]Researchers: Prof Phillip Bird (Principal investigator) , Dr Paulus Mrass
Brief description Cytotoxic T cells (CTL) are white blood cells that move in an orchestrated way into body tissues to target, and destroy, virus-infected or cancer cells. Destruction of these abnormal cells is achieved when they ingest cytotoxic enzymes (proteases) released by CTL. We propose that one of these cytotoxins, granzyme B, has a dual function, and that it is also involved in helping CTL to efficiently move towards the target cells by clearing a path through the local tissue structure.
Funding Amount $AUD 605,962.99
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 1007830
- PURL : https://purl.org/au-research/grants/nhmrc/1007830
