grant

IMMUNOPHILINS IN STEROID RECEPTOR- AND TISSUE-SPECIFIC ACTIONS: IMPLICATIONS FOR TREATMENT OF STEROID-BASED DISEASE [ 2008 - 2010 ]

Also known as: IMMUNOPHILIN COCHAPERONES IN STEROID HORMONE ACTION

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/513869]

Researchers: Prof Thomas Ratajczak (Principal investigator) ,  Prof Didier Picard

Brief description To convert steroid hormone signals in the cell steroid receptors rely on Hsp90 molecular chaperone machinery that is essential for receptor function and in particular 'helper' cohaperones that form part of receptor- Hsp90 complexes and fine-tune receptor responses to hormone. The present study addresses the fundamental role of the receptor helper' chaperone cyclophilin 40. Our study may have important implications for the treatment of steroid-based disease.

Funding Amount $AUD 480,211.67

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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