Immune-modifying-particle-induced Tregs induce remission in experimental autoimmune encephalomyelitis [ 2015 - 2018 ]

Research Grant

Researchers: Prof Nicholas King (Principal investigator) ,  Dr Daniel Getts

Brief description Multiple Sclerosis is a debilitating autoimmune disease of the central nervous system. Disease is the result of inflammatory monocyte-derived dendritic cells that migrate from the blood into the brain, where they stimulate T cells to attack myelin sheaths around neurons. Our novel therapy, known as immune modulating micro-particles reduces monocyte migration and disease in a mouse model, we hypothesize, by inducing immunosuppressive T regulatory cells that control attacking T cells in MS.

Funding Amount $AUD 512,440.84

Funding Scheme Project Grants

Notes Standard Project Grant