grant

Imaging genetics in schizophrenia and bipolar disorder: Adjudicating neurocognitive endophenotypes [ 2010 - 2015 ]

Also known as: Shared genes and cognition in schizophrenia and bipolar disorder

Funded by National Health and Medical Research Council
Managed by University of New South Wales
Provided by   National Health and Medical Research Council

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/630471]

Researchers: A/Pr Melissa Green (Principal investigator)

Brief description Schizophrenia and bipolar disorder share some common genes and cognitive deficits, yet manifest differently in terms of symptom expression, illness course, and functional impact. This research tests the assertion that genes implicated as common to these conditions may code for impairments in prefrontal cognitive and sub-cortical emotion processing. We also examine whether between-diagnosis distinctions in these brain responses may be mediated by hypothalamic-pituitary-adrenal axis functioning.

Funding Amount $AUD 569,873.46

Funding Scheme NHMRC Project Grants

Notes New Investigator Grant

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Related Publications

  • Associated with Genome-wide supported variant MIR137 and severe negative symptoms predict membership of an impaired cognitive subtype of schizophrenia
    handle : 1959.13/1300769

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Subjects
Biological Sciences | Genetics | Neurogenetics | bipolar disorder | brain function | cognition | cognition in schizphrenia and bipolar disorder | genetic predisposition | genetics, polygenetic inheritance | neuropsychological impairments | prefrontal cortex | psychosis | schizophrenia |
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