IL-6 as the key inflammatory mediator controlling GVHD [ 2014 - 2016 ]

Research Grant

Researchers: Prof Geoff Hill (Principal investigator) ,  A/Pr Kelli Macdonald ,  Dr Siok-Keen Tey

Brief description Allogeneic haematopoietic stem cell transplantation (SCT) is a curative treatment for blood cancers. Graft-versus-host disease (GVHD) is a major limitation which occurs when the newly transplanted immune system mounts a rejection response against the recipient and is responsible for the death of up to 40% of transplant recipients. These studies will optimize a new approach to prevent GVHD focusing on a protein called interleukin-6. Ultimately, it is anticipated such approaches will improve the overall survival of patients with blood cancers.

Funding Amount $AUD 592,049.40

Funding Scheme Project Grants

Notes Standard Project Grant