Identifying Novel Biosynthetic Pathways in Mycobacteria using DNA Microarray Technology [ 2003-01-01 - 2007-12-31 ]

Research Grant

Researchers: Dr Paul Crellin (Chief Investigator) ,  Prof Ross Coppel (Chief Investigator)

Brief description Identifying Novel Biosynthetic Pathways in Mycobacteria using DNA Microarray Technology. DNA microarrays are a powerful new bioinformatics-based technology and an ideal tool for characterising complex biosynthetic pathways since the expression of all genes in the bacterial genome can be monitored in a single experiment. In this project we aim to construct and use a DNA microarray to identify novel biosynthetic pathways in mycobacteria. Of particular interest are pathways used to create components of the highly complex and poorly characterised cell wall. Since this structure is unique in the bacterial world, we expect to identify and characterise pathways that are unique to mycobacteria.

Funding Amount $200,000

Funding Scheme Discovery Projects

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