grant

Identifying the molecular mechanisms of synergistic and antagonistic drug-drug interactions in combination chemotherapies [ 2015 - 2020 ]

Also known as: Understanding the mechanisms of drug-drug synergy in combination chemotherapy

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1072965]

Researchers: Dr Adam Palmer (Principal investigator)

Brief description Drug combinations in chemotherapy hold promise for more effective treatments and for overcoming drug resistance, but the search for effective combinations is challenging. The combination therapy R-CHOP is often curative for Diffuse Large B-cell Lymphoma (DLBCL). Both cellular drug interactions and evolutionary drug interactions will be quantified in DLBCL cells, to understand the defining features of effective combinations and guide the future rational design of combinations.

Funding Amount $AUD 412,685.35

Funding Scheme Early Career Fellowships

Notes CJ Martin Biomedical ECF

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Identifiers
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ACN 633 798 857