grant

Identifying the mechanism of the G2 phase UV checkpoint and repair response commonly defective in melanoma [ 2014 - 2016 ]

Also known as: Defining a defective UV response in melanoma

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1064807]

Researchers: Prof Brian Gabrielli (Principal investigator) ,  Dr Sandra Pavey

Brief description The UV component of sunlight is the major environmental factor driving the development of melanoma. UV radiation can directly mutate genes resulting in their inability to perform normal functions which may contribute to cancer. Despite the high number of mutations directly attributable to UV radiation, the mechanisms known to repair these mutations are generally normal in melanoma. This research will investigate a repair mechanism we have identified that is commonly defective in melanomas.

Funding Amount $AUD 569,656.10

Funding Scheme Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857