grant

Identification of telomere-specific recombination pathways [ 2008 - 2010 ]

Also known as: Telomere-specific recombination

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/502600]

Researchers: A/Pr Jorg Heierhorst (Principal investigator)

Brief description Human cells stop to grow when the natural ends of chromosomes become too short. One way of how cancer cells evade this growth arrest is by using a copy-mechanism to extend short chromosome ends. Ironically, this copy mechanism is usually used by cells to keep the structure of chromosomes intact in order to prevent mutations that cause cancer. Here we will study a novel protein that contributes to the copy mechanism at short chromosome ends, but not as much in normal mutation prevention.

Funding Amount $AUD 540,075.08

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857