grant

Identification of the pain pathway from the rectum and its mechanisms of activation [ 2009 - 2011 ]

Also known as: Pain pathway following rectal distension

Funded by National Health and Medical Research Council
Managed by Flinders University
Managed by The Flinders University of South Australia
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/535033]

Researchers: Prof Nicholas Spencer (Principal investigator) ,  Dr Vladimir Zagorodnyuk ,  Prof Simon Brookes

Brief description Abdominal pain is one of the most common reasons why patients seek medical attention. It is now known that irritable bowel syndrome (IBS) is one of the major causes of abdominal pain, but the reason why people experience pain from the gut is not known. This project will identify which sensory nerves in the gut wall signal pain to the spinal cord during conditions that mimic IBS and the precise mechanisms that activate these sensory neurons during IBS-like inflammation will be investigated.

Funding Amount $AUD 566,931.70

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Subjects
Biomedical and Clinical Sciences | Nutrition and Dietetics | Sport and Exercise Nutrition | gastroenterology | gastrointestinal motility | inflammation | inflammatory bowel disease | irritable bowel syndrome | pain | pain transmission | sensory function | sensory transduction |
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