Identification of PACE-1 as a novel therapeutic target for the treatment of prostate cancer [ 2012 - 2015 ]

Research Grant

Researchers: Dr Ming Tat (Patrick) Ling (Principal investigator) ,  Prof Pamela Russell ,  Prof Ronald Quinn

Brief description Advanced prostate cancer (PCa) remains the major therapeutic challenge since neither surgery nor systemic therapies are effective at this stage. Recently, we identified a protein called PACE-1 that is essential for PCa cell survival. We plan to investigate the roles of PACE-1 in the development and progression of prostate cancer. We will then test if PACE-1 inactivation alone or in combination with systemic cancer therapies will inhibit prostate tumor growth and disease progression.

Funding Amount $AUD 606,144.50

Funding Scheme Project Grants

Notes Standard Project Grant