grant

Identification of novel therapeutic binding sites on glycine receptors by high throughput screening [ 2008 - 2010 ]

Also known as: Discovering new binding sites for analgesic and anti-spasticity drugs

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/511169]

Researchers: Prof Joseph Lynch (Principal investigator)

Brief description Glycine receptors mediate inhibitory neurotransmission in the nervous system. They provide fresh therapeutic targets for chronic inflammatory pain and muscle spasticity. Here we identify 5 compounds that may be appropriate as leads for discovering novel therapies for these disorders. We will use automated high throughput screening methods to discover how these drugs interact with the receptor. This will narrow down the search for the next generation of analgesic and muscle relaxant drugs.

Funding Amount $AUD 542,017.81

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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