Identification of novel mechanisms governing stage-specific regulation of the human globin genes [ 2011 - 2013 ]

Research Grant

Researchers: Prof Stephen Jane (Principal investigator) ,  A/Pr Ian Street ,  Dr John Parisot ,  Dr Quan Zhao

Brief description Hemoglobin is the major protein in red blood cells and is essential for the transport of oxygen from the lungs to the tissues. The disorders of hemoglobin production are the commonest genetic diseases world-wide. These diseases can be markedly improved with elevation of the form of hemoglobin produced by the developing embryo, embryonic hemoglobin. We have identified a key factor important for fetal gene expression. Our goal is to translate these findings into therapies for the globin disorders.

Funding Amount $AUD 577,889.10

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant