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grant

Identification of the molecular mechanisms by which mutations in FHL1 lead to protein misfolding and skeletal muscle disease [ 2011 - 2013 ]

Also known as: Role of FHL1 in skeletal muscle disease

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1010655]

Researchers: Prof Christina Mitchell (Principal investigator) ,  Dr Meagan Mcgrath

Brief description Skeletal muscle diseases result in debilitating muscle loss and may result from an error (mutation) within a gene. Mutations in FHL1 were identified as the cause of four different muscle diseases. Using purified FHL1, skeletal muscle cells and animal models we will investigate how FHL1 mutations cause muscle wasting, and loss of muscle strength.

Funding Amount $AUD 609,424.46

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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