grant

The identification of male meiosis genes using a new mouse line and human genome scans for gene copy number variations [ 2008 - 2010 ]

Also known as: The regulation of meiosis in mice and men

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/490916]

Researchers: Prof Moira O'Bryan (Principal investigator)

Brief description Infertility affects 1 in 25 Australian men and meiosis is a key process in male fertility, yet we know very little about the mechanisms that control it. We will use a new point mutant mouse model of meisois failure to identify a novel regulator of male fertility. Further, we hypothesize that changes in gene copy number will lead to meiosis arrest and infertility in some men. Such variations will be assessed through a whole genome scan of a unique set of infertile men.

Funding Amount $AUD 604,793.48

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857