Identification of interferon stimulated genes that limit HCV replication and predict therapeutic outcome [ 2008 - 2010 ]

Also known as: Host genes that control HCV replication and predict treatment response

Research Grant

[Cite as]

Researchers: A/Pr Michael Beard (Principal investigator) ,  Dr Karla Helbig Prof Eric Gowans

Brief description The only treatment for hepatitis C is Interferon-ribavirin combination therapy. Interferon works by stimulating the liver cells to produce antiviral proteins that can control hepatitis C virus replication, however we do not know which proteins are responsible. The aim of this proposal is to identify those proteins that can limit HCV replication using both a laboratory based and clinical approach and to identify markers that will predict treatment outcome.

Funding Amount $AUD 389,224.94

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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